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| Cat.No | ACP09570 | Target Name | KLK5 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 23-293 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9Y337 |
|---|
Uniprot Id
Q9Y337
Target Species
Human
Target Name
KLK5
Target Full Name
Kallikrein-5
Target Function
May be involved in desquamation.
Target Subcellular Location
Secreted.
Target Protein Families
Peptidase S1 family, Kallikrein subfamily
Target Tissue Specificity
Expressed in skin, breast, brain and testis. Expressed at the stratum granulosum of palmar skin.
Target Synonyms
HK5; Kallikrein 5; Kallikrein L2; Kallikrein like 2; Kallikrein like protein 2; Kallikrein related peptidase 5; Kallikrein-5; Kallikrein-like protein 2; Kallikrein5; KLK 5; KLK L2; KLK-L2; KLK5; KLK5_HUMAN; KLKL 2; KLKL2; SCTE; Stratum corneum tryptic enzyme; UNQ570/PRO1132
Target Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein.
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