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| Cat.No | ACP23703 | Target Name | SERPINA4 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 21-427 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P29622 |
|---|
Uniprot Id
P29622
Target Species
Human
Target Name
SERPINA4
Target Full Name
Kallistatin
Target Function
Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.
Target Subcellular Location
Secreted.
Target Protein Families
Serpin family
Target Tissue Specificity
Expressed by the liver and secreted in plasma.
Target Synonyms
KAIN_HUMAN; KAL; Kallikrein binding protein; Kallikrein inhibitor; Kallistatin; KBP; KLST ; KST; MGC108582; Peptidase inhibitor 4; PI-4; PI4; Protease inhibitor 4 (kallistatin); Protease inhibitor 4; Serine (or cysteine) proteinase inhibitor; clade A (alpha 1 antiproteinase; antitrypsin); member 4; Serpin A4; Serpin peptidase inhibitor clade A member 4; Serpin peptidase inhibitor; clade A (alpha 1 antiproteinase; antitrypsin); member 4; SERPINA4; Tissue kallistatin inhibitor
Target Background
Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Located in extracellular exosome. Biomarker of diabetic retinopathy.
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