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| Cat.No | ACP15095 | Target Name | KLHL7 |
|---|---|---|---|
| Target Synonyms | KLHL7Kelch-like protein 7 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-586 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8IXQ5 |
|---|
Uniprot Id
Q8IXQ5
Target Species
Human
Target Name
KLHL7
Target Full Name
Kelch-like protein 7
Target Function
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex. The BCR(KLHL7) complex acts by mediating ubiquitination and subsequent degradation of substrate proteins. Probably mediates 'Lys-48'-linked ubiquitination.
Target Involvement
Cold-induced sweating syndrome 3 (CISS3); Retinitis pigmentosa 42 (RP42)
Target Subcellular Location
Nucleus. Cytoplasm.
Target Tissue Specificity
Widely expressed, with highest levels in adult and fetal heart, CNS and adult testis.
Target Synonyms
KLHL7Kelch-like protein 7
Target Background
This gene encodes a BTB-Kelch-related protein. The encoded protein may be involved in protein degradation. Mutations in this gene have been associated with retinitis pigmentosa 42.
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