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Recombinant Human Kelch repeat and BTB domain-containing protein 8 (KBTBD8)

ACP13643

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Specifications

Cat.No	ACP13643	Target Name	KBTBD8
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	1-601	Protein Length	Full length protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q8NFY9

Background Information

Uniprot Id

Q8NFY9
Target Species

Human
Target Name

KBTBD8
Target Full Name

Kelch repeat and BTB domain-containing protein 8
Target Function

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of neural crest specification. The BCR(KBTBD8) complex acts by mediating monoubiquitination of NOLC1 and TCOF1: monoubiquitination promotes the formation of a NOLC1-TCOF1 complex that acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification.
Target Subcellular Location

Cytoplasm, cytoskeleton, spindle. Golgi apparatus.
Target Protein Families

KBTBD8 family
Target Synonyms

AU040152; FLJ57592; KBTB8_HUMAN; Kbtbd8; Kelch repeat and BTB (POZ) domain containing 8 ; Kelch repeat and BTB domain containing protein 8; Kelch repeat and BTB domain-containing protein 8; KIAA1842; MGC91215; mKIAA1842; OTTHUMP00000213470; RGD1563166; SSEC 51; SSEC51; T cell activation kelch repeat protein; T-cell activation Kelch repeat protein; TA KRP; TA-KRP; Takrp

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Recombinant Human Kelch repeat and BTB domain-containing protein 8 (KBTBD8)

Specifications

Immunogen Information

Inquire Recombinant Human Kelch repeat and BTB domain-containing protein 8 (KBTBD8) Now

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