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| Cat.No | ACP22544 | Target Name | KRTAP12-2 |
|---|---|---|---|
| Target Synonyms | KRTAP12-2; KAP12.2; KRTAP12.2Keratin-associated protein 12-2; High sulfur keratin-associated protein 12.2; Keratin-associated protein 12.2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-146 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P59991 |
|---|
Uniprot Id
P59991
Target Species
Human
Target Name
KRTAP12-2
Target Full Name
Keratin-associated protein 12-2
Target Function
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Target Protein Families
KRTAP type 12 family
Target Tissue Specificity
Restricted to a narrow region of the hair fiber cuticle, lying approximately 20 cell layers above the apex of the dermal papilla of the hair root; not detected in any other tissues.
Target Synonyms
KRTAP12-2; KAP12.2; KRTAP12.2Keratin-associated protein 12-2; High sulfur keratin-associated protein 12.2; Keratin-associated protein 12.2
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