Recombinant Human Keratin, type II cytoskeletal 74 (KRT74)

ACP16266

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Specifications

Cat.No	ACP16266	Target Name	KRT74
Target Synonyms	KRT74; K6IRS4; KB37; KRT5C; KRT6IRS4; Keratin; type II cytoskeletal 74; Cytokeratin-74; CK-74; Keratin-5c; K5C; Keratin-74; K74; Type II inner root sheath-specific keratin-K6irs4; Type-II keratin Kb37	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-529
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q7RTS7

Background Information

Uniprot Id

Q7RTS7
Target Species

Human
Target Name

KRT74
Target Full Name

Keratin, type II cytoskeletal 74
Target Function

Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle.
Target Involvement

Woolly hair autosomal dominant (ADWH); Hypotrichosis 3 (HYPT3); Ectodermal dysplasia 7, hair/nail type (ECTD7)
Target Protein Families

Intermediate filament family
Target Tissue Specificity

Highly expressed in hair follicles from scalp. In hair, it is specifically present in the inner root sheath (IRS) of the hair follicle. Present in the IRS Huxley layer, but not in Henle layer or cuticle of the IRS. In the IRS Huxley layer, it is expressed
Target Synonyms

KRT74; K6IRS4; KB37; KRT5C; KRT6IRS4; Keratin; type II cytoskeletal 74; Cytokeratin-74; CK-74; Keratin-5c; K5C; Keratin-74; K74; Type II inner root sheath-specific keratin-K6irs4; Type-II keratin Kb37

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Recombinant Human Keratin, type II cytoskeletal 74 (KRT74)

Specifications

Immunogen Information

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