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| Cat.No | ACP03569 | Target Name | KHK |
|---|---|---|---|
| Target Synonyms | EC 2.7.1.3; Fructokinase; Hepatic fructokinase; Ketohexokinase; Ketohexokinase isoform a; KHK; KHK_HUMAN | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-298aa |
| Mol Weight | 59.7kDa | Protein Length | Full Length of Isoform 2 |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P50053 |
|---|
Uniprot Id
P50053
Target Species
Human
Target Name
KHK
Target Full Name
Ketohexokinase
Target Function
Catalyzes the phosphorylation of the ketose sugar fructose to fructose-1-phosphate.
Target Involvement
Fructosuria (FRUCT)
Target Protein Families
Carbohydrate kinase PfkB family
Target Tissue Specificity
Most abundant in liver, kidney, gut, spleen and pancreas. Low levels also found in adrenal, muscle, brain and eye.
Target Research Area
Signal Transduction
Target Synonyms
EC 2.7.1.3; Fructokinase; Hepatic fructokinase; Ketohexokinase; Ketohexokinase isoform a; KHK; KHK_HUMAN
Target Background
This gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively spliced transcript variants encoding different isoforms have been identified.
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