Recombinant Human Kinesin-like protein KIF20B (KIF20B), Truncated

Cat.No	ACP14041	Target Name	KIF20B
Target Synonyms	Cancer/testis antigen 90; CT90; KI20B_HUMAN; KIF20B; Kinesin-like protein KIF20B; Kinesin-related motor interacting with PIN1; KRMP1; M-phase phosphoprotein 1; MPHOSPH1; MPP 1; Mpp1	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP14041

Target Name

KIF20B

Target Synonyms

Cancer/testis antigen 90; CT90; KI20B_HUMAN; KIF20B; Kinesin-like protein KIF20B; Kinesin-related motor interacting with PIN1; KRMP1; M-phase phosphoprotein 1; MPHOSPH1; MPP 1; Mpp1

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Protein Length

Partial

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q96Q89

Background Information

Uniprot Id

Q96Q89
Target Species

Human
Target Name

KIF20B
Target Full Name

Kinesin-like protein KIF20B
Target Function

Plus-end-directed motor enzyme that is required for completion of cytokinesis. Required for proper midbody organization and abscission in polarized cortical stem cells. Plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. Participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. Involved in cerebral cortex growth. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression.
Target Subcellular Location

Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus, nucleolus. Nucleus, nucleoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Midbody. Cell projection, axon. Cell projection, growth cone.
Target Protein Families

TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family
Target Tissue Specificity

Brain, ovary, kidney and testis (at protein level). Overexpressed in bladder cancer cells (at protein level). Expressed in testis. Overexpressed in bladder cancer cells.
Target Synonyms

Cancer/testis antigen 90; CT90; KI20B_HUMAN; KIF20B; Kinesin-like protein KIF20B; Kinesin-related motor interacting with PIN1; KRMP1; M-phase phosphoprotein 1; MPHOSPH1; MPP 1; Mpp1
Target Background

Enables several functions, including WW domain binding activity; plus-end-directed microtubule motor activity; and protein homodimerization activity. Involved in positive regulation of cell population proliferation and positive regulation of cytokinesis. Located in several cellular components, including microtubule cytoskeleton; midbody; and nuclear lumen.

Recombinant Human Kinesin-like protein KIF20B (KIF20B), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Kinesin-like protein KIF20B (KIF20B), Truncated Now

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