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Recombinant Human Kinesin-like protein KIF2B (KIF2B)

ACP14004

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP14004 Target NameKIF2B
Target SynonymsKIF2BKinesin-like protein KIF2BFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-673
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8N4N8
Background Information
  • Uniprot Id

    Q8N4N8

  • Target Species

    Human

  • Target Name

    KIF2B

  • Target Full Name

    Kinesin-like protein KIF2B

  • Target Function

    Plus end-directed microtubule-dependent motor required for spindle assembly and chromosome movement. Has microtubule depolymerization activity. Plays a role in chromosome congression.

  • Target Subcellular Location

    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Association with kinetochore is transient.

  • Target Protein Families

    TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family, MCAK/KIF2 subfamily

  • Target Tissue Specificity

    Highest level in lung. High level in ovary, moderate levels in heart, kidney, placenta, skeletal muscle and spleen (at protein level). Pancreas and spleen express a shorter isoform (at protein level).

  • Target Synonyms

    KIF2BKinesin-like protein KIF2B

  • Target Background

    Predicted to enable microtubule binding activity and microtubule motor activity. Involved in metaphase plate congression; microtubule depolymerization; and regulation of chromosome segregation. Located in intercellular bridge; mitotic spindle; and nucleolus.

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