Recombinant Human Krueppel-like factor 10 (KLF10)

Cat.No	ACP17981	Target Name	KLF10
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	1-480	Protein Length	Full length protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP17981

Target Name

KLF10

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Expression Range

1-480

Protein Length

Full length protein

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q13118

Background Information

Uniprot Id

Q13118
Target Species

Human
Target Name

KLF10
Target Full Name

Krueppel-like factor 10
Target Function

Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. Plays a role in the regulation of the circadian clock; binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity. Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver. Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis. May play a role in the cell cycle regulation.
Target Subcellular Location

Nucleus.
Target Protein Families

Sp1 C2H2-type zinc-finger protein family
Target Synonyms

Early growth response; alpha; Early growth response; alpha like; EGR A; EGR alpha ; EGR(A); EGR-alpha; EGRA; Egral; EGRalpha; Gdnfif; KLF 10; KLF10; KLF10_HUMAN; Krueppel like factor 10; Krueppel like factor10; Krueppel-like factor 10; Kruppel like factor 10; mGIF; TGF-beta- inducible early gene; TGFB inducible early growth response 1; TGFB inducible early growth response; TGFB inducible early growth response protein 1; TGFB-inducible early growth response protein 1; TIEG 1; TIEG; TIEG-1; TIEG1; Transforming growth factor beta inducible early growth response; Transforming growth factor beta inducible early growth response protein 1; Transforming growth factor-beta-inducible early growth response protein 1; Zinc finger transcription factor TIEG
Target Background

This gene encodes a member of a family of proteins that feature C2H2-type zinc finger domains. The encoded protein is a transcriptional repressor that acts as an effector of transforming growth factor beta signaling. Activity of this protein may inhibit the growth of cancers, particularly pancreatic cancer. Alternative splicing results in multiple transcript variants.

Recombinant Human Krueppel-like factor 10 (KLF10)

Specifications

Immunogen Information

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