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| Cat.No | ACP21362 | Target Name | SPINT1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 36-529 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O43278 |
|---|
Uniprot Id
O43278
Target Species
Human
Target Name
SPINT1
Target Full Name
Kunitz-type protease inhibitor 1
Target Function
Inhibitor of HGF activator. Also acts as an inhibitor of matriptase (ST14).
Target Subcellular Location
Secreted.
Target Synonyms
HAI 1; HAI; HAI-1; HAI1; Hepatocyte growth factor activator inhibitor type 1; Kunitz type protease inhibitor 1; Kunitz-type protease inhibitor 1; MANSC2; Serine peptidase inhibitor Kunitz type 1; SPINT1; SPIT1_HUMAN
Target Background
The protein encoded by this gene is a member of the Kunitz family of serine protease inhibitors. The protein is a potent inhibitor specific for HGF activator and is thought to be involved in the regulation of the proteolytic activation of HGF in injured tissues. Alternative splicing results in multiple variants encoding different isoforms.
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