Recombinant Human Lactosylceramide 4-alpha-galactosyltransferase (A4GALT), Truncated

Cat.No	ACP11772	Target Name	A4GALT
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP11772

Target Name

A4GALT

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Protein Length

Partial

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q9NPC4

Background Information

Uniprot Id

Q9NPC4
Target Species

Human
Target Name

A4GALT
Target Full Name

Lactosylceramide 4-alpha-galactosyltransferase
Target Function

Catalyzes the transfer of galactose from UDP-alpha-D-galactose to lactosylceramide/beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide(d18:1(4E)) to produce globotriaosylceramide/globoside Gb3Cer (d18:1(4E)). Also able to transfer galactose to galactosylceramide/beta-D-Gal-(1<->1')-Cer. Globoside Gb3Cer is a glycosphingolipid of the globo serie, one of the major types of neutral root structures of glycosphingolipids, that constitute a significant portion of mammalian cell membranes. Globotriaosylceramide/globoside Gb3Cer in blood and tissue cell membranes is the antigen Pk of blood histogroup P.; (Microbial infection) Globotriaosylceramide is one of the cellular ligands for bacterial verotoxins.
Target Subcellular Location

Golgi apparatus membrane; Single-pass type II membrane protein.
Target Protein Families

Glycosyltransferase 32 family
Target Tissue Specificity

Ubiquitous. Highly expressed in kidney, heart, spleen, liver, testis and placenta.
Target Synonyms

4 N acetylglucosaminyltransferase; 4-galactosyltransferase; 4-N-acetylglucosaminyltransferase; A14GALT; A4GALT; A4GALT1; A4GAT_HUMAN; Alpha 1 4 galactosyltransferase; Alpha 1 4 N acetylglucosaminyltransferase; Alpha-1; Alpha4Gal T1; Alpha4Gal-T1; CD77 synthase; Gb3 synthase; Gb3S; Globotriaosylceramide synthase; Lactosylceramide 4 alpha galactosyltransferase; Lactosylceramide 4-alpha-galactosyltransferase; P blood group (P one antigen); P(k) antigen synthase; P1; P1/Pk synthase; PK; UDP galactose beta D galactosyl beta1 R 4 alpha D galactosyltransferase; UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase
Target Background

The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. This protein, a type II membrane protein found in the Golgi, is also required for the synthesis of the bacterial verotoxins receptor. Alternatively spliced transcript variants have been found for this gene.

Recombinant Human Lactosylceramide 4-alpha-galactosyltransferase (A4GALT), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Lactosylceramide 4-alpha-galactosyltransferase (A4GALT), Truncated Now

Related Products