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| Cat.No | ACP09100 | Target Name | LCE3A |
|---|---|---|---|
| Target Synonyms | LCE3A; LEP13Late cornified envelope protein 3A; Late envelope protein 13 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-89aa |
| Mol Weight | 12.6kDa | Protein Length | Full length |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5TA76 |
|---|
Uniprot Id
Q5TA76
Target Species
Human
Target Name
LCE3A
Target Full Name
Late cornified envelope protein 3A
Target Function
A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens.
Target Protein Families
LCE family
Target Tissue Specificity
Skin-specific. Expression was readily detected in adult trunk skin, adult arm skin, fetal skin, penal skin, vulva, esophagus and tongue. Not expressed in the cervix, rectum, lung, colon, or placenta.
Target Research Area
Signal Transduction
Target Synonyms
LCE3A; LEP13Late cornified envelope protein 3A; Late envelope protein 13
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