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| Cat.No | ACP11242 | Target Name | ZFYVE28 |
|---|---|---|---|
| Target Synonyms | ZFYVE28; KIAA1643; LST2Lateral signaling target protein 2 homolog; hLst2; Zinc finger FYVE domain-containing protein 28 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9HCC9 |
|---|
Uniprot Id
Q9HCC9
Target Species
Human
Target Name
ZFYVE28
Target Full Name
Lateral signaling target protein 2 homolog
Target Function
Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated.
Target Subcellular Location
Cytoplasm, cytosol. Early endosome membrane. Note=Localizes to early endosome membrane in absence of Lys-87 monoubiquitination. Localizes to cytosol when monoubiquitinated.
Target Protein Families
Lst-2 family
Target Synonyms
ZFYVE28; KIAA1643; LST2Lateral signaling target protein 2 homolog; hLst2; Zinc finger FYVE domain-containing protein 28
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