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Recombinant Human Lens fiber membrane intrinsic protein (LIM2), Truncated

ACP06914

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Specifications

Cat.No	ACP06914	Target Name	LIM2
Target Synonyms	LIM2; Lens fiber membrane intrinsic protein; MP18; MP19; MP20	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	P55344

Background Information

Uniprot Id

P55344
Target Species

Human
Target Name

LIM2
Target Full Name

Lens fiber membrane intrinsic protein
Target Function

Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis.
Target Involvement

Cataract, multiple types 19 (CTRCT19)
Target Subcellular Location

Membrane; Multi-pass membrane protein.
Target Protein Families

PMP-22/EMP/MP20 family
Target Tissue Specificity

Eye lens specific.
Target Synonyms

LIM2; Lens fiber membrane intrinsic protein; MP18; MP19; MP20
Target Background

This gene encodes an eye lens-specific protein found at the junctions of lens fiber cells, where it may contribute to cell junctional organization. It acts as a receptor for calmodulin, and may play an important role in both lens development and cataractogenesis. Mutations in this gene have been associated with cataract formation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Recombinant Human Lens fiber membrane intrinsic protein (LIM2), Truncated

Specifications

Immunogen Information

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