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| Cat.No | ACP16013 | Target Name | LETMD1 |
|---|---|---|---|
| Target Synonyms | LETMD1LETM1 domain-containing protein 1; Cervical cancer 1 proto-oncogene protein p40; Cervical cancer proto-oncogene 2 protein; HCCR-1; HCRR-2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6P1Q0 |
|---|
Uniprot Id
Q6P1Q0
Target Species
Human
Target Name
LETMD1
Target Full Name
LETM1 domain-containing protein 1
Target Function
Involved in tumorigenesis and may function as a negative regulator of the p53/TP53.
Target Subcellular Location
Mitochondrion outer membrane; Single-pass membrane protein.
Target Tissue Specificity
Kidney, liver, skeletal muscle, heart and brain. Overexpressed in various tumors including leukemia, lymphoma, and carcinomas of the breast, kidney, ovary, stomach, colon and uterine cervix.
Target Synonyms
LETMD1LETM1 domain-containing protein 1; Cervical cancer 1 proto-oncogene protein p40; Cervical cancer proto-oncogene 2 protein; HCCR-1; HCRR-2
Target Background
This gene encodes a mitochondrial outer membrane protein. It has a potential role in tumorigenesis, which may result from negative regulation of the p53 tumor suppressor gene. Alternatively spliced transcript variants have been noted for this gene.
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