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| Cat.No | ACP11521 | Target Name | LRRC19 |
|---|---|---|---|
| Target Synonyms | FLJ21302; Leucine rich repeat containing 19; leucine rich repeat containing protein 19; Leucine-rich repeat-containing protein 19; LRC19_HUMAN; LRRC 19; LRRC19 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H756 |
|---|
Uniprot Id
Q9H756
Target Species
Human
Target Name
LRRC19
Target Full Name
Leucine-rich repeat-containing protein 19
Target Function
Pathogen-recognition receptor which mediates the activation of TRAF2- and TRAF6 NF-kappa-B signaling pathways and induces the expression of proinflammatory cytokines. In kidney, prevents infection by uropathogenic bacteria by inducing the production of cytokines, chemokines and antimicrobial substances. In gut, involved in host-microbiota interactions, plays a critical role in promoting the recruitment of immune cells and intestinal inflammation.
Target Subcellular Location
Membrane; Single-pass type I membrane protein.
Target Tissue Specificity
Expressed in renal collecting duct epithelial cells.
Target Synonyms
FLJ21302; Leucine rich repeat containing 19; leucine rich repeat containing protein 19; Leucine-rich repeat-containing protein 19; LRC19_HUMAN; LRRC 19; LRRC19
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