Recombinant Human Leucine-rich repeat-containing protein 8B (LRRC8B), Truncated

ACP06095

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Specifications

Cat.No	ACP06095	Target Name	LRRC8B
Target Synonyms	LRRC8B; KIAA0231; UNQ6413/PRO21207; Volume-regulated anion channel subunit LRRC8B; Leucine-rich repeat-containing protein 8B; T-cell activation leucine repeat-rich protein; TA-LRRP	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q6P9F7

Background Information

Uniprot Id

Q6P9F7
Target Species

Human
Target Name

LRRC8B
Target Full Name

Volume-regulated anion channel subunit LRRC8B
Target Function

Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and can also conduct organic osmolytes like taurine. Channel activity requires LRRC8A plus at least one other family member (LRRC8B, LRRC8C, LRRC8D or LRRC8E); channel characteristics depend on the precise subunit composition.
Target Subcellular Location

Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane.
Target Protein Families

LRRC8 family
Target Synonyms

LRRC8B; KIAA0231; UNQ6413/PRO21207; Volume-regulated anion channel subunit LRRC8B; Leucine-rich repeat-containing protein 8B; T-cell activation leucine repeat-rich protein; TA-LRRP

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Recombinant Human Leucine-rich repeat-containing protein 8B (LRRC8B), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Leucine-rich repeat-containing protein 8B (LRRC8B), Truncated Now

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