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Recombinant Human Leukocyte immunoglobulin-like receptor subfamily A member 3 (LILRA3)

ACP14291

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP14291 Target NameLILRA3
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range24-439Protein LengthFull Length of Mature Protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8N6C8
Background Information
  • Uniprot Id

    Q8N6C8

  • Target Species

    Human

  • Target Name

    LILRA3

  • Target Full Name

    Leukocyte immunoglobulin-like receptor subfamily A member 3

  • Target Function

    Acts as soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes.

  • Target Subcellular Location

    Secreted.

  • Target Tissue Specificity

    Detected in B-cells, and at lower levels in natural killer (NK) cells. Detected in peripheral blood monocytes and lung.

  • Target Synonyms

    CD 85E; CD85 antigen-like family member E; CD85e; CD85e antigen; e3; HM 31; HM 43; HM31; HM43; ILT 6; ILT-6; ILT6; Immunoglobulin like transcript 6; Immunoglobulin-like transcript 6; Leucocyte immunoglobulin like receptor; Leukocyte immunoglobulin like receptor 4; Leukocyte immunoglobulin like receptor A3; Leukocyte immunoglobulin like receptor subfamily A (without TM domain) member 3; Leukocyte immunoglobulin like receptor subfamily A member 3; Leukocyte immunoglobulin-like receptor 4; Leukocyte immunoglobulin-like receptor subfamily A member 3; LILRA 3; LILRA3; LIR 4; LIR-4; LIR4; LIRA3_HUMAN; Monocyte inhibitory receptor HM43/HM31

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