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| Cat.No | ACP16637 | Target Name | LRIF1 |
|---|---|---|---|
| Target Synonyms | LRIF1; C1orf103; RIF1Ligand-dependent nuclear receptor-interacting factor 1; HP1-binding protein enriched in inactive X chromosome protein 1; HBiX1; Receptor-interacting factor 1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-769 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5T3J3 |
|---|
Uniprot Id
Q5T3J3
Target Species
Human
Target Name
LRIF1
Target Full Name
Ligand-dependent nuclear receptor-interacting factor 1
Target Function
Together with SMCHD1, involved in chromosome X inactivation in females by promoting the compaction of heterochromatin. Also able to repress the ligand-induced transcriptional activity of retinoic acid receptor alpha (RARA), possibly through direct recruitment of histone deacetylases.
Target Subcellular Location
Chromosome. Nucleus matrix.
Target Protein Families
LRIF1 family
Target Tissue Specificity
Widely expressed, with the highest expression levels in heart, liver and placenta.
Target Synonyms
LRIF1; C1orf103; RIF1Ligand-dependent nuclear receptor-interacting factor 1; HP1-binding protein enriched in inactive X chromosome protein 1; HBiX1; Receptor-interacting factor 1
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