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| Cat.No | ACP21081 | Target Name | PPFIA2 |
|---|---|---|---|
| Target Synonyms | alpha 2; PTPRF interacting protein alpha 2; PTPRF-interacting protein alpha-2, f polypeptide (PTPRF), interacting protein (liprin), receptor type | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O75334 |
|---|
Uniprot Id
O75334
Target Species
Human
Target Name
PPFIA2
Target Full Name
Liprin-alpha-2
Target Function
Alters PTPRF cellular localization and induces PTPRF clustering. May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates. In neuronal cells, is a scaffolding protein in the dendritic spines which acts as immobile postsynaptic post able to recruit KIF1A-driven dense core vesicles to dendritic spines.
Target Subcellular Location
Cytoplasm. Cell surface. Cell projection, dendritic spine. Note=Colocalizes with PTPRF at the cell surface.
Target Protein Families
Liprin family, Liprin-alpha subfamily
Target Tissue Specificity
Expressed only in brain.
Target Synonyms
LIPA2_HUMAN; Liprin-alpha-2; PPFIA2; Protein tyrosine phosphatase receptor type f polypeptide interacting protein alpha 2; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2; Protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2; PTPRF interacting protein alpha 2; PTPRF-interacting protein alpha-2
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