Home Products Recombinant Human Lysine-specific demethylase 6B (KDM6B), Truncated

Recombinant Human Lysine-specific demethylase 6B (KDM6B), Truncated

ACP01580

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Specifications

Cat.No	ACP01580	Target Name	KDM6B
Form	Liquid or Lyophilized powder	Expression System	E.coli
Expression Range	1176-1505aa	Mol Weight	41.5 kDa
Protein Length	Partial	Purity	Greater than 85% as determined by SDS-PAGE.
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O15054

Background Information

Uniprot Id

O15054
Target Species

Human
Target Name

KDM6B
Target Full Name

Lysine-specific demethylase 6B
Target Function

Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation. Plays a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression by acting as a link between T-box factors and the SMARCA4-containing SWI/SNF remodeling complex.
Target Subcellular Location

Nucleus.
Target Protein Families

UTX family
Target Research Area

Epigenetics and Nuclear Signaling
Target Synonyms

Histone demethylase JMJD3; JmjC domain containing protein 3; JmjC domain-containing protein 3; Jumonji D3; Jumonji domain containing 3; Jumonji domain containing 3 histone lysine demethylase; Jumonji domain containing protein 3; Jumonji domain-containing protein 3; Kdm6b; KDM6B_HUMAN; KIAA0346; Lysine demethylase 6B; Lysine K specific demethylase 6B; Lysine specific demethylase 6B ; Lysine-specific demethylase 6B

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Recombinant Human Lysine-specific demethylase 6B (KDM6B), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Lysine-specific demethylase 6B (KDM6B), Truncated Now

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