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Recombinant Human MAD2L1-binding protein (MAD2L1BP)

ACP17728

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Specifications

Cat.No	ACP17728	Target Name	MAD2L1BP
Target Synonyms	Caught by MAD2 protein; CMT2; dJ261G23.1 ; KIAA0110; MAD2L1 binding protein; MAD2L1 binding protein isoform 2; MAD2L1-binding protein; Mad2l1bp; MD2BP_HUMAN; MGC11282; OTTHUMP00000016496; RP1 261G23.6	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-274
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q15013

Background Information

Uniprot Id

Q15013
Target Species

Human
Target Name

MAD2L1BP
Target Full Name

MAD2L1-binding protein
Target Function

May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex.
Target Subcellular Location

Nucleus. Cytoplasm, cytoskeleton, spindle. Note=During early mitosis, unevenly distributed throughout the nucleoplasm. From metaphase to anaphase, concentrated on the spindle.
Target Protein Families

MAD2L1BP family
Target Synonyms

Caught by MAD2 protein; CMT2; dJ261G23.1 ; KIAA0110; MAD2L1 binding protein; MAD2L1 binding protein isoform 2; MAD2L1-binding protein; Mad2l1bp; MD2BP_HUMAN; MGC11282; OTTHUMP00000016496; RP1 261G23.6
Target Background

The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

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Recombinant Human MAD2L1-binding protein (MAD2L1BP)

Specifications

Immunogen Information

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