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| Cat.No | ACP06036 | Target Name | MFSD12 |
|---|---|---|---|
| Target Synonyms | MFSD12; C19orf28; Major facilitator superfamily domain-containing protein 12 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6NUT3 |
|---|
Uniprot Id
Q6NUT3
Target Species
Human
Target Name
MFSD12
Target Full Name
Major facilitator superfamily domain-containing protein 12
Target Function
Transporter that mediates the import of cysteine into melanosomes, thereby regulating skin pigmentation. In melanosomes, cysteine import is required both for normal levels of cystine, the oxidized dimer of cysteine, and provide cysteine for the production of the cysteinyldopas used in pheomelanin synthesis, thereby regulating skin pigmentation. Also catalyzes import of cysteine into lysosomes in non-pigmented cells.
Target Subcellular Location
Melanosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein.
Target Protein Families
Major facilitator superfamily
Target Tissue Specificity
Widely expressed, with high expression in primary melanocytes.
Target Synonyms
MFSD12; C19orf28; Major facilitator superfamily domain-containing protein 12
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