Recombinant Human Mannose-binding protein C (MBL2)

Discover the power of our high-quality Recombinant Human MBL2 protein, engineered to provide optimal performance in immunology research. Expressed in E. coli, this protein represents the full length of the mature protein (2-115aa) and features an N-terminal 6xHis-tag for seamless purification. With a purity greater than 90% as determined by SDS-PAGE, our MBL2 protein ensures dependable and consistent results in your experimental endeavors. Investigate the diverse roles of MBL2 in innate immunity, inflammation, and host-pathogen interactions using this exceptional recombinant protein. Available in both liquid and lyophilized powder forms, our Recombinant Human MBL2 protein is a valuable asset for enhancing your research capabilities.

ACP04843

Discover the power of our high-quality Recombinant Human MBL2 protein, engineered to provide optimal performance in immunology research. Expressed in E. coli, this protein represents the full length of the mature protein (2-115aa) and features an N-terminal 6xHis-tag for seamless purification. With a purity greater than 90% as determined by SDS-PAGE, our MBL2 protein ensures dependable and consistent results in your experimental endeavors.
Investigate the diverse roles of MBL2 in innate immunity, inflammation, and host-pathogen interactions using this exceptional recombinant protein. Available in both liquid and lyophilized powder forms, our Recombinant Human MBL2 protein is a valuable asset for enhancing your research capabilities.

Number

Cat.No	ACP04843	Target Name	MBL2
Form	Liquid or Lyophilized powder	Expression System	Yeast
Expression Range	21-248aa	Mol Weight	26.0kDa
Protein Length	Full Length of Mature Protein	Purity	Greater than 90% as determined by SDS-PAGE.
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP04843

Target Name

MBL2

Form

Liquid or Lyophilized powder

Expression System

Yeast

Expression Range

21-248aa

Mol Weight

26.0kDa

Protein Length

Full Length of Mature Protein

Purity

Greater than 90% as determined by SDS-PAGE.

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	P11226

Background Information

Uniprot Id

P11226
Target Species

Human
Target Name

MBL2
Target Full Name

Mannose-binding protein C
Target Function

Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.
Target Subcellular Location

Secreted.
Target Tissue Specificity

Plasma protein produced mainly in the liver.
Target Research Area

Immunology
Target Synonyms

COLEC 1; COLEC1; Collectin-1; HSMBPC; Lectin; mannose-binding; soluble; 2; Mannan binding lectin; Mannan binding protein; Mannan-binding protein; Mannose binding lectin (protein C) 2 soluble; Mannose binding lectin (protein C) 2; soluble (opsonic defect); Mannose binding lectin (protein C) 2; soluble; Mannose binding lectin 2 soluble; Mannose binding lectin 2; soluble (opsonic defect); Mannose binding lectin; Mannose binding lectin protein C2 soluble opsonic defect; Mannose binding protein; Mannose binding protein C; Mannose binding protein C precursor ; Mannose binding protein; serum; Mannose-binding lectin; Mannose-binding protein C; MBL 2; MBL; MBL2; MBL2_HUMAN; MBL2D; MBP 1; MBP; MBP C; MBP-C; MBP1; MBPB; MBPC; MBPD; MGC116832; MGC116833; Opsonic defect; protein C; Soluble mannose binding lectin
Target Background

This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes and binds to mannose and N-acetylglucosamine on many microorganisms, including bacteria, yeast, and viruses including influenza virus, HIV and SARS-CoV. This binding activates the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases.

Recombinant Human Mannose-binding protein C (MBL2)

Specifications

Immunogen Information

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