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| Cat.No | ACP10229 | Target Name | SPG21 |
|---|---|---|---|
| Target Synonyms | SPG21; ACP33; BM-019; GL010; Maspardin; Acid cluster protein 33; Spastic paraplegia 21 autosomal recessive Mast syndrome protein; Spastic paraplegia 21 protein | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-308 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NZD8 |
|---|
Uniprot Id
Q9NZD8
Target Species
Human
Target Name
SPG21
Target Full Name
Maspardin
Target Function
May play a role as a negative regulatory factor in CD4-dependent T-cell activation.
Target Involvement
Spastic paraplegia 21, autosomal recessive (SPG21)
Target Subcellular Location
Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Note=Partially localized in the cytosol but also accumulated on an intracellular vesicular compartment. Colocalizes with CD4 on endosomal/trans-Golgi network.
Target Protein Families
AB hydrolase superfamily
Target Tissue Specificity
Expressed in all tissues tested, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Expressed in J.CaM1.6, HuT 78 and HeLa cell lines (at protein level).
Target Synonyms
SPG21; ACP33; BM-019; GL010; Maspardin; Acid cluster protein 33; Spastic paraplegia 21 autosomal recessive Mast syndrome protein; Spastic paraplegia 21 protein
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