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Recombinant Human Matrilin-3 (MATN3)

ACP04995

Number
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Specifications


Cat.No ACP04995 Target NameMATN3
Target SynonymsAV009181; DIPOA; EDM5; HOA; MATN3; MATN3_HUMAN; Matrilin 3; Matrilin-3; OADIP; OS2FormLiquid or Lyophilized powder
Expression SystemE.coliExpression Range29-486aa
Mol Weight57.2 kDaProtein LengthFull Length of Mature Protein
PurityGreater than 90% as determined by SDS-PAGE.Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDO15232
Background Information
  • Uniprot Id

    O15232

  • Target Species

    Human

  • Target Name

    MATN3

  • Target Full Name

    Matrilin-3

  • Target Function

    Major component of the extracellular matrix of cartilage and may play a role in the formation of extracellular filamentous networks.

  • Target Involvement

    Multiple epiphyseal dysplasia 5 (EDM5); Spondyloepimetaphyseal dysplasia MATN3-related (SEMD-MATN3); Osteoarthritis 2 (OS2)

  • Target Subcellular Location

    Secreted.

  • Target Tissue Specificity

    Expressed only in cartilaginous tissues, such as vertebrae, ribs and shoulders.

  • Target Research Area

    Others

  • Target Synonyms

    AV009181; DIPOA; EDM5; HOA; MATN3; MATN3_HUMAN; Matrilin 3; Matrilin-3; OADIP; OS2

  • Target Background

    This gene encodes a member of von Willebrand factor A domain containing protein family. This family of proteins is thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This protein contains two von Willebrand factor A domains; it is present in the cartilage extracellular matrix and has a role in the development and homeostasis of cartilage and bone. Mutations in this gene result in multiple epiphyseal dysplasia.

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