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| Cat.No | ACP04995 | Target Name | MATN3 |
|---|---|---|---|
| Target Synonyms | AV009181; DIPOA; EDM5; HOA; MATN3; MATN3_HUMAN; Matrilin 3; Matrilin-3; OADIP; OS2 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 29-486aa |
| Mol Weight | 57.2 kDa | Protein Length | Full Length of Mature Protein |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O15232 |
|---|
Uniprot Id
O15232
Target Species
Human
Target Name
MATN3
Target Full Name
Matrilin-3
Target Function
Major component of the extracellular matrix of cartilage and may play a role in the formation of extracellular filamentous networks.
Target Involvement
Multiple epiphyseal dysplasia 5 (EDM5); Spondyloepimetaphyseal dysplasia MATN3-related (SEMD-MATN3); Osteoarthritis 2 (OS2)
Target Subcellular Location
Secreted.
Target Tissue Specificity
Expressed only in cartilaginous tissues, such as vertebrae, ribs and shoulders.
Target Research Area
Others
Target Synonyms
AV009181; DIPOA; EDM5; HOA; MATN3; MATN3_HUMAN; Matrilin 3; Matrilin-3; OADIP; OS2
Target Background
This gene encodes a member of von Willebrand factor A domain containing protein family. This family of proteins is thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This protein contains two von Willebrand factor A domains; it is present in the cartilage extracellular matrix and has a role in the development and homeostasis of cartilage and bone. Mutations in this gene result in multiple epiphyseal dysplasia.
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