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Recombinant Human Matrix metalloproteinase-21 (MMP21)

ACP12844

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP12844 Target NameMMP21
Target SynonymsMMP21Matrix metalloproteinase-21; MMP-21; EC 3.4.24.-FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range145-569
Protein LengthFull Length of Mature ProteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8N119
Background Information
  • Uniprot Id

    Q8N119

  • Target Species

    Human

  • Target Name

    MMP21

  • Target Full Name

    Matrix metalloproteinase-21

  • Target Function

    Plays a specialized role in the generation of left-right asymmetry during embryogenesis. May act as a negative regulator of the NOTCH-signaling pathway. Cleaves alpha-1-antitrypsin.

  • Target Involvement

    Heterotaxy, visceral, 7, autosomal (HTX7)

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    Peptidase M10A family

  • Target Tissue Specificity

    Identified in fetal brain, kidney and liver. In adult tissues found primarily in ovary, kidney, liver, lung, placenta, brain and peripheral blood leukocytes. Expressed as well in various cancer cell lines.

  • Target Synonyms

    MMP21Matrix metalloproteinase-21; MMP-21; EC 3.4.24.-

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