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| Cat.No | ACP05472 | Target Name | XK |
|---|---|---|---|
| Target Synonyms | XK; XKR1; XRG1; Membrane transport protein XK; Kell complex 37 kDa component; Kx antigen; XK-related protein 1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P51811 |
|---|
Uniprot Id
P51811
Target Species
Human
Target Name
XK
Target Full Name
Endoplasmic reticulum membrane adapter protein XK
Target Function
May be involved in sodium-dependent transport of neutral amino acids or oligopeptides.
Target Involvement
McLeod syndrome (MLS)
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
XK family
Target Tissue Specificity
High levels in skeletal muscle, heart, brain, and pancreas; low levels in placenta, lung, liver, and kidney.
Target Synonyms
XK; XKR1; XRG1; Membrane transport protein XK; Kell complex 37 kDa component; Kx antigen; XK-related protein 1
Target Background
This locus controls the synthesis of the Kell blood group 'precursor substance' (Kx). Mutations in this gene have been associated with McLeod syndrome, an X-linked, recessive disorder characterized by abnormalities in the neuromuscular and hematopoietic systems. The encoded protein has structural characteristics of prokaryotic and eukaryotic membrane transport proteins.
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