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| Cat.No | ACP00795 | Target Name | STEAP1 |
|---|---|---|---|
| Target Synonyms | Six-transmembrane epithelial antigen of prostate 1 | Form | Liquid or Lyophilized powder |
| Expression System | in vitro E.coli expression system | Expression Range | 1-339aa |
| Mol Weight | 41.2 kDa | Protein Length | Full length |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9UHE8 |
|---|
Uniprot Id
Q9UHE8
Target Species
Human
Target Name
STEAP1
Target Full Name
STEAP1 protein
Target Function
Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor.
Target Subcellular Location
Endosome membrane; Multi-pass membrane protein.
Target Protein Families
STEAP family
Target Tissue Specificity
Ubiquitously expressed. Highly expressed in prostate tumors.
Target Research Area
Epigenetics and Nuclear Signaling, Transport
Target Synonyms
STEAP1; PRSS24; STEAP; Metalloreductase STEAP1; Six-transmembrane epithelial antigen of prostate 1
Target Background
This gene is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six-transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell-cell junctions.
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