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| Cat.No | ACP16334 | Target Name | METAP1D |
|---|---|---|---|
| Target Synonyms | METAP1D; MAP1DMethionine aminopeptidase 1D; mitochondrial; MAP 1D; MetAP 1D; EC 3.4.11.18; Methionyl aminopeptidase type 1D; mitochondrial; Peptidase M 1D | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 20-335 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6UB28 |
|---|
Uniprot Id
Q6UB28
Target Species
Human
Target Name
METAP1D
Target Full Name
Methionine aminopeptidase 1D, mitochondrial
Target Function
Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. May play a role in colon tumorigenesis.
Target Subcellular Location
Mitochondrion.
Target Protein Families
Peptidase M24A family, Methionine aminopeptidase type 1 subfamily
Target Tissue Specificity
Overexpressed in colon cancer cell lines and colon tumors as compared to normal tissues (at protein level).
Target Synonyms
METAP1D; MAP1DMethionine aminopeptidase 1D; mitochondrial; MAP 1D; MetAP 1D; EC 3.4.11.18; Methionyl aminopeptidase type 1D; mitochondrial; Peptidase M 1D
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