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Recombinant Human Methionine-R-sulfoxide reductase B3 (MSRB3)

ACP03287

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Specifications

Cat.No	ACP03287	Target Name	MSRB3
Target Synonyms	Autosomal Recessive 74; DFNB74; FLJ36866; Methionine R sulfoxide reductase B mitochondrial; Methionine sulfoxide reductase B3; Methionine-R-sulfoxide reductase B3; MsrB3; MSRB3_HUMAN, Deafness	Form	Liquid or Lyophilized powder
Expression System	E.coli	Expression Range	1-185aa
Mol Weight	47.0kDa	Protein Length	Full Length of Isoform 2
Purity	Greater than 90% as determined by SDS-PAGE.	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q8IXL7

Background Information

Uniprot Id

Q8IXL7
Target Species

Human
Target Name

MSRB3
Target Full Name

Methionine-R-sulfoxide reductase B3
Target Function

Catalyzes the reduction of free and protein-bound methionine sulfoxide to methionine. Isoform 2 is essential for hearing.
Target Involvement

Deafness, autosomal recessive, 74 (DFNB74)
Target Subcellular Location

[Isoform 1]: Endoplasmic reticulum.; [Isoform 2]: Mitochondrion.
Target Protein Families

MsrB Met sulfoxide reductase family
Target Tissue Specificity

Widely expressed.
Target Research Area

Signal Transduction
Target Synonyms

Deafness, Autosomal Recessive 74; DFNB74; FLJ36866; Methionine R sulfoxide reductase B mitochondrial; Methionine sulfoxide reductase B3; Methionine-R-sulfoxide reductase B3; MsrB3; MSRB3_HUMAN
Target Background

The protein encoded by this gene catalyzes the reduction of methionine sulfoxide to methionine. This enzyme acts as a monomer and requires zinc as a cofactor. Several transcript variants encoding two different isoforms have been found for this gene. One of the isoforms localizes to mitochondria while the other localizes to endoplasmic reticula.

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Recombinant Human Methionine-R-sulfoxide reductase B3 (MSRB3)

Specifications

Immunogen Information

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