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| Cat.No | ACP13450 | Target Name | MCEE |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 37-176 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96PE7 |
|---|
Uniprot Id
Q96PE7
Target Species
Human
Target Name
MCEE
Target Full Name
Methylmalonyl-CoA epimerase, mitochondrial
Target Function
Methylmalonyl-CoA epimerase involved in propionyl-CoA metabolism.
Target Involvement
Methylmalonyl-CoA epimerase deficiency (MCEED)
Target Subcellular Location
Mitochondrion.
Target Protein Families
Glyoxalase I family
Target Synonyms
DL methylmalonyl CoA racemase; DL-methylmalonyl-CoA racemase; EC 5.1.99.1; GLOD2 ; Glyoxalase domain containing 2 ; MCEE; MCEE_HUMAN; Methylmalonyl CoA epimerase; Methylmalonyl-CoA epimerase; methylmalonyl-CoA epimerase; mitochondrial; mitochondrial; OTTHUMP00000160122
Target Background
The product of this gene catalyzes the interconversion of D- and L-methylmalonyl-CoA during the degradation of branched chain amino acids. odd chain-length fatty acids, and other metabolites. Mutations in this gene result in methylmalonyl-CoA epimerase deficiency, which is presented as mild to moderate methylmalonic aciduria.
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