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Recombinant Human MICAL-like protein 2 (MICALL2), Truncated

ACP14939

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP14939 Target NameMICALL2
Target SynonymsMICALL2; JRAB; MICAL-like protein 2; Junctional Rab13-binding protein; Molecule interacting with CasL-like 2; MICAL-L2FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8IY33
Background Information
  • Uniprot Id

    Q8IY33

  • Target Species

    Human

  • Target Name

    MICALL2

  • Target Full Name

    MICAL-like protein 2

  • Target Function

    Effector of small Rab GTPases which is involved in junctional complexes assembly through the regulation of cell adhesion molecules transport to the plasma membrane and actin cytoskeleton reorganization. Regulates the endocytic recycling of occludins, claudins and E-cadherin to the plasma membrane and may thereby regulate the establishment of tight junctions and adherens junctions. In parallel, may regulate actin cytoskeleton reorganization directly through interaction with F-actin or indirectly through actinins and filamins. Most probably involved in the processes of epithelial cell differentiation, cell spreading and neurite outgrowth

  • Target Subcellular Location

    Cell membrane; Peripheral membrane protein. Cell junction, tight junction. Recycling endosome. Cell projection. Cytoplasm, cytoskeleton. Cytoplasm, cytosol.

  • Target Synonyms

    MICALL2; JRAB; MICAL-like protein 2; Junctional Rab13-binding protein; Molecule interacting with CasL-like 2; MICAL-L2

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