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| Cat.No | ACP17322 | Target Name | MIIP |
|---|---|---|---|
| Target Synonyms | MIIP; IIP45; Migration and invasion-inhibitory protein; IGFBP2-binding protein; Invasion-inhibitory protein 45; IIp45 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-388 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5JXC2 |
|---|
Uniprot Id
Q5JXC2
Target Species
Human
Target Name
MIIP
Target Full Name
Migration and invasion-inhibitory protein
Target Function
Inhibits glioma cells invasion and down-regulates adhesion- and motility-associated genes such as NFKB2 and ICAM1. Exhibits opposing effects to IGFBP2 on cell invasion.
Target Tissue Specificity
Ubiquitous. Isoform 1 is expressed in brain but underexpressed in glioma tissues, at protein level. Isoform 2 is not detected in normal organs, but is expressed in gliomas with increasing levels with glioma progression. On the contrary, at protein level,
Target Synonyms
MIIP; IIP45; Migration and invasion-inhibitory protein; IGFBP2-binding protein; Invasion-inhibitory protein 45; IIp45
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