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| Cat.No | ACP09224 | Target Name | OGN |
|---|---|---|---|
| Target Synonyms | Corneal keratan sulfate proteoglycan; DKFZP586P2421; MIME_HUMAN; Mimecan; Mimecan proteoglycan; OG; OGN; OIF; Osteoglycin; Osteoinductive factor; SLRR3A | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 21-298 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P20774 |
|---|
Uniprot Id
P20774
Target Species
Human
Target Name
OGN
Target Full Name
Mimecan
Target Function
Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.
Target Subcellular Location
Secreted, extracellular space, extracellular matrix.
Target Protein Families
Small leucine-rich proteoglycan (SLRP) family, SLRP class III subfamily
Target Tissue Specificity
Bone.
Target Research Area
Signal Transduction
Target Synonyms
Corneal keratan sulfate proteoglycan; DKFZP586P2421; MIME_HUMAN; Mimecan; Mimecan proteoglycan; OG; OGN; OIF; Osteoglycin; Osteoinductive factor; SLRR3A
Target Background
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded protein induces ectopic bone formation in conjunction with transforming growth factor beta and may regulate osteoblast differentiation. High expression of the encoded protein may be associated with elevated heart left ventricular mass. Alternative splicing results in multiple transcript variants.
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