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| Cat.No | ACP17549 | Target Name | ALDH1L2 |
|---|---|---|---|
| Target Synonyms | 10 formyltetrahydrofolate dehydrogenase ALDH1L2; 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE, member L2; Aldehyde dehydrogenase family 1 member L2; Aldehyde dehydrogenase family 1 member L2, MITOCHONDRIAL; AL1L2_HUMAN; Aldehyde dehydrogenase 1 family, mitochondrial; ALDH1L2; Mitochondrial 10 formyltetrahydrofolate dehydrogenase; Mitochondrial 10 FTHFDH; mtFDH; Probable 10-formyltetrahydrofolate dehydrogenase ALDH1L2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q3SY69 |
|---|
Uniprot Id
Q3SY69
Target Species
Human
Target Name
ALDH1L2
Target Full Name
Mitochondrial 10-formyltetrahydrofolate dehydrogenase
Target Subcellular Location
Mitochondrion.
Target Protein Families
GART family; Aldehyde dehydrogenase family, ALDH1L subfamily
Target Tissue Specificity
Highly expressed in pancreas, heart, brain and skeletal muscle.
Target Synonyms
10 formyltetrahydrofolate dehydrogenase ALDH1L2; 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE, MITOCHONDRIAL; AL1L2_HUMAN; Aldehyde dehydrogenase 1 family, member L2; Aldehyde dehydrogenase family 1 member L2; Aldehyde dehydrogenase family 1 member L2, mitochondrial; ALDH1L2; Mitochondrial 10 formyltetrahydrofolate dehydrogenase; Mitochondrial 10 FTHFDH; mtFDH; Probable 10-formyltetrahydrofolate dehydrogenase ALDH1L2
Target Background
This gene encodes a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene.
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