Recombinant Human Mitochondrial import inner membrane translocase subunit Tim13 (TIMM13)

Cat.No	ACP09678	Target Name	TIMM13
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	1-95	Protein Length	Full length protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP09678

Target Name

TIMM13

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Expression Range

1-95

Protein Length

Full length protein

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q9Y5L4

Background Information

Uniprot Id

Q9Y5L4
Target Species

Human
Target Name

TIMM13
Target Full Name

Mitochondrial import inner membrane translocase subunit Tim13
Target Function

Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins.
Target Subcellular Location

Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Target Protein Families

Small Tim family
Target Tissue Specificity

Ubiquitous, with highest expression in heart, kidney, liver and skeletal muscle.
Target Synonyms

Mitochondrial import inner membrane translocase subunit TIM13; Mitochondrial import inner membrane translocase subunit Tim13B; ppv1; TIM 13; TIM13; TIM13_HUMAN; TIM13B; TIMM 13; Timm13; TIMM13A; TIMM13B; Translocase of inner mitochondrial membrane 13 homolog
Target Background

This gene encodes a member of the evolutionarily conserved TIMM (translocase of inner mitochondrial membrane) family of proteins that function as chaperones in the import of proteins from the cytoplasm into the mitochondrial inner membrane. Proteins of this family play a role in collecting substrate proteins from the translocase of the outer mitochondrial membrane (TOM) complex and delivering them to either the sorting and assembly machinery in the outer mitochondrial membrane (SAM) complex or the TIMM22 complex in the inner mitochondrial membrane. The encoded protein and the translocase of mitochondrial inner membrane 8a protein form a 70 kDa complex in the intermembrane space.

Recombinant Human Mitochondrial import inner membrane translocase subunit Tim13 (TIMM13)

Specifications

Immunogen Information

Inquire Recombinant Human Mitochondrial import inner membrane translocase subunit Tim13 (TIMM13) Now

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