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Recombinant Human Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22), Truncated

ACP07108

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP07108 Target NameTimm22
Target SynonymsTIMM22; TEX4; TIM22; Mitochondrial import inner membrane translocase subunit Tim22; Testis-expressed protein 4FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9Y584
Background Information
  • Uniprot Id

    Q9Y584

  • Target Species

    Human

  • Target Name

    TIMM22

  • Target Full Name

    Mitochondrial import inner membrane translocase subunit Tim22

  • Target Function

    Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.

  • Target Subcellular Location

    Mitochondrion inner membrane; Multi-pass membrane protein.

  • Target Protein Families

    Tim17/Tim22/Tim23 family

  • Target Synonyms

    TIMM22; TEX4; TIM22; Mitochondrial import inner membrane translocase subunit Tim22; Testis-expressed protein 4

  • Target Background

    Multipass transmembrane proteins are brought into mitochondria and inserted into the mitochondrial inner membrane by way of the TIM22 complex. This complex has six subunits and is a twin-pore translocase. The protein encoded by this gene is a subunit of TIM22 and represents the voltage-activated and signal-gated channel.

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