Recombinant Human Mitochondrial import receptor subunit TOM22 homolog (TOMM22), Truncated

Uniprot Id

Q9NS69

Target Species

Human

Target Name

TOMM22

Target Full Name

Mitochondrial import receptor subunit TOM22 homolog

Target Function

Central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with the peripheral receptor TOM20 functions as the transit peptide receptor and facilitates the movement of preproteins into the translocation pore. Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases.

Target Subcellular Location

Mitochondrion outer membrane; Single-pass membrane protein.

Target Protein Families

Tom22 family

Target Tissue Specificity

Ubiquitous.

Target Synonyms

TOMM22; TOM22; Mitochondrial import receptor subunit TOM22 homolog; hTom22; 1C9-2; Translocase of outer membrane 22 kDa subunit homolog

Target Background

The protein encoded by this gene is an integral membrane protein of the mitochondrial outer membrane. The encoded protein interacts with TOMM20 and TOMM40, and forms a complex with several other proteins to import cytosolic preproteins into the mitochondrion.