Recombinant Human Modulator of apoptosis 1 (MOAP1)

ACP03388

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Specifications

Cat.No	ACP03388	Target Name	MOAP1
Target Synonyms	MAP 1; MAP-1; MAP1; MOAP1; MOAP1_HUMAN; Modulator of apoptosis 1; Modulator of Apoptosis; Paraneoplastic antigen like 4; Paraneoplastic antigen Ma4; paraneoplastic Ma antigen family member 4; PNMA4	Form	Liquid or Lyophilized powder
Expression System	E.coli	Expression Range	1-351aa
Mol Weight	66.5kDa	Protein Length	Full length
Purity	Greater than 90% as determined by SDS-PAGE.	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q96BY2

Background Information

Uniprot Id

Q96BY2
Target Species

Human
Target Name

MOAP1
Target Full Name

Modulator of apoptosis 1
Target Function

Required for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation.
Target Protein Families

PNMA family
Target Tissue Specificity

Widely expressed, with high levels in heart and brain.
Target Research Area

Cell Biology
Target Synonyms

MAP 1; MAP-1; MAP1; MOAP1; MOAP1_HUMAN; Modulator of apoptosis 1; Modulator of Apoptosis; Paraneoplastic antigen like 4; Paraneoplastic antigen Ma4; paraneoplastic Ma antigen family member 4; PNMA4
Target Background

The protein encoded by this gene was identified by its interaction with apoptosis regulator BAX protein. This protein contains a Bcl-2 homology 3 (BH3)-like motif, which is required for the association with BAX. When overexpressed, this gene has been shown to mediate caspase-dependent apoptosis.

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Recombinant Human Modulator of apoptosis 1 (MOAP1)

Specifications

Immunogen Information

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