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Recombinant Human Myosin-IIIb (MYO3B), Truncated

ACP13280

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Specifications

Cat.No	ACP13280	Target Name	MYO3B
Target Synonyms	A430065P19Rik; Myo3b; MYO3B_HUMAN; Myosin IIIB; Myosin-IIIB; RGD1560313; RP23-337L20.2	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q8WXR4

Background Information

Uniprot Id

Q8WXR4
Target Species

Human
Target Name

MYO3B
Target Full Name

Myosin-IIIb
Target Function

Probable actin-based motor with a protein kinase activity. Required for normal cochlear hair bundle development and hearing. Plays an important role in the early steps of cochlear hair bundle morphogenesis. Influences the number and lengths of stereocilia to be produced and limits the growth of microvilli within the forming auditory hair bundles thereby contributing to the architecture of the hair bundle, including its staircase pattern. Involved in the elongation of actin in stereocilia tips by transporting the actin regulatory factor ESPN to the plus ends of actin filaments.
Target Subcellular Location

Cytoplasm, cytoskeleton. Cell projection, stereocilium.
Target Protein Families

TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; Protein kinase superfamily, STE Ser/Thr protein kinase family
Target Tissue Specificity

Expressed in retina, kidney and testis.
Target Synonyms

A430065P19Rik; Myo3b; MYO3B_HUMAN; Myosin IIIB; Myosin-IIIB; RGD1560313; RP23-337L20.2

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Recombinant Human Myosin-IIIb (MYO3B), Truncated

Specifications

Immunogen Information

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