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| Cat.No | ACP03496 | Target Name | MYL3 |
|---|---|---|---|
| Target Synonyms | alkali, alkali; myosin, B; Myosin light chain 3; Myosin, light chain 1, light chain 3, light polypeptide 3, skeletal, slow; myosin, slow; OTTHUMP00000165922; Slow skeletal ventricular myosin alkali light chain 3; slow-twitch muscle B/ventricular isoform; Ventricular/slow twitch myosin alkali light chain; VLC1, ventricular, ventricular; myosin | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-195aa |
| Mol Weight | 48.8kDa | Protein Length | Full length |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P08590 |
|---|
Uniprot Id
P08590
Target Species
Human
Target Name
MYL3
Target Full Name
Myosin light chain 3
Target Function
Regulatory light chain of myosin. Does not bind calcium.
Target Involvement
Cardiomyopathy, familial hypertrophic 8 (CMH8)
Target Synonyms
Cardiac myosin light chain 1; CMH8 ; CMLC1; ELC of myosin; Essential light chain of myosin; MLC1SB; MLC1V; MYL3; MYL3_HUMAN; Myosin light chain 1; Myosin light chain 1 slow twitch muscle B/ventricular isoform; Myosin light chain 1 slow, B; Myosin light chain 3; Myosin, light chain 1, ventricular; myosin, light chain 3, alkali, ventricular, skeletal, slow; myosin, light polypeptide 3, alkali; myosin, light polypeptide 3, alkali, ventricular, skeletal, slow; OTTHUMP00000165922; Slow skeletal ventricular myosin alkali light chain 3; slow-twitch muscle B/ventricular isoform; Ventricular/slow twitch myosin alkali light chain; VLC1
Target Background
MYL3 encodes myosin light chain 3, an alkali light chain also referred to in the literature as both the ventricular isoform and the slow skeletal muscle isoform. Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy.
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