Recombinant Human Myosin regulatory light polypeptide 9 (MYL9)

Uniprot Id

P24844

Target Species

Human

Target Name

MYL9

Target Full Name

Myosin regulatory light polypeptide 9

Target Function

Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion. In myoblasts, may regulate PIEZO1-dependent cortical actomyosin assembly involved in myotube formation.

Target Subcellular Location

Cytoplasm, cytoskeleton. Cytoplasm, cell cortex.

Target Tissue Specificity

Smooth muscle tissues and in some, but not all, nonmuscle cells.

Target Research Area

Cancer

Target Synonyms

20 kDa myosin light chain; Human 20kDa myosin light chain (MLC2) mRNA complete cds; LC20; MGC3505 ; MLC 2 ; MLC-2C; MLC2 ; MLY 9; MRLC1 ; MYL9; MYL9_HUMAN; Myosin light chain 9 regulatory; Myosin light polypeptide 9 regulatory; myosin regulatory light chain 1; Myosin regulatory light chain 2; Myosin regulatory light chain 2 smooth muscle isoform; Myosin regulatory light chain 9; Myosin regulatory light chain MRLC1; Myosin regulatory light polypeptide 9; Myosin RLC; Myosin vascular smooth muscle light chain 2; MYRL2 ; OTTHUMP00000030857; smooth muscle isoform

Target Background

Myosin, a structural component of muscle, consists of two heavy chains and four light chains. The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads. The encoded protein binds calcium and is activated by myosin light chain kinase. Two transcript variants encoding different isoforms have been found for this gene.