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| Cat.No | ACP15511 | Target Name | GALNT7 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q86SF2 |
|---|
Uniprot Id
Q86SF2
Target Species
Human
Target Name
GALNT7
Target Full Name
N-acetylgalactosaminyltransferase 7
Target Function
Glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide. In contrast to other proteins of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on the protein receptor, but instead requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified.
Target Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein.
Target Protein Families
Glycosyltransferase 2 family, GalNAc-T subfamily
Target Tissue Specificity
Widely expressed. Expressed in uterus, retina, kidney, small intestine, omentum, stomach and CNS.
Target Synonyms
GalNAc T7; GalNAc-T7; GalNAcT7; GALNT 7; Galnt7; GALT7_HUMAN; N acetylgalactosaminyltransferase 7; N-acetylgalactosaminyltransferase 7; Polypeptide GalNAc transferase 7; Polypeptide N acetylgalactosaminyltransferase 7; pp GaNTase 7; pp-GaNTase 7; Protein UDP acetylgalactosaminyltransferase 7; Protein-UDP acetylgalactosaminyltransferase 7; UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 7; UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 7; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7
Target Background
This gene encodes GalNAc transferase 7, a member of the GalNAc-transferase family. The enzyme encoded by this gene controls the initiation step of mucin-type O-linked protein glycosylation and transfer of N-acetylgalactosamine to serine and threonine amino acid residues. This enzyme is a type II transmembrane protein and shares common sequence motifs with other family members. Unlike other family members, this enzyme shows exclusive specificity for partially GalNAc-glycosylated acceptor substrates and shows no activity with non-glycosylated peptides. This protein may function as a follow-up enzyme in the initiation step of O-glycosylation.
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