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| Cat.No | ACP17131 | Target Name | ESCO2 |
|---|---|---|---|
| Target Synonyms | ESCO2N-acetyltransferase ESCO2; EC 2.3.1.-; Establishment factor-like protein 2; EFO2; EFO2p; hEFO2; Establishment of cohesion 1 homolog 2; ECO1 homolog 2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-601 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q56NI9 |
|---|
Uniprot Id
Q56NI9
Target Species
Human
Target Name
ESCO2
Target Full Name
N-acetyltransferase ESCO2
Target Function
Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during the S phase. Acetylates the cohesin component SMC3.
Target Involvement
Roberts syndrome (RBS); SC phocomelia syndrome (SCPS)
Target Subcellular Location
Nucleus. Chromosome.
Target Protein Families
Acetyltransferase family, ECO subfamily
Target Tissue Specificity
Widely expressed in fetal tissues. In adult, it is expressed in thymus, placenta and small intestine.
Target Synonyms
ESCO2N-acetyltransferase ESCO2; EC 2.3.1.-; Establishment factor-like protein 2; EFO2; EFO2p; hEFO2; Establishment of cohesion 1 homolog 2; ECO1 homolog 2
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