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| Cat.No | ACP15371 | Target Name | NECAB2 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-386 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q7Z6G3 |
|---|
Uniprot Id
Q7Z6G3
Target Species
Human
Target Name
NECAB2
Target Full Name
N-terminal EF-hand calcium-binding protein 2
Target Function
May act as a signaling scaffold protein that senses intracellular calcium. Can modulate ligand-induced internalization of ADORA2A and coupling efficiency of mGluR5/GRM5; for both receptors may regulate signaling activity such as promoting MAPK1/3 (ERK1/2) activation.
Target Subcellular Location
Cytoplasm. Cell projection, dendrite. Cell projection, axon. Cell membrane.
Target Tissue Specificity
Expressed in brain. Expressed in the spinal dorsal horn with especially strong expression in lamina IIi; found in excitory synaptic boutons and in ependymal cells (at protein level).
Target Synonyms
EF hand calcium binding protein 2; EF-hand calcium-binding protein 2; N-terminal EF-hand calcium-binding protein 2; NECA2_HUMAN; Necab2; Neuronal calcium binding protein 2; Neuronal calcium-binding protein 2; Stip 2 ; Stip-2; Stip2 ; Synaptotagmin interacting protein 2; Synaptotagmin-interacting protein 2
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