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Recombinant Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 (NDUFAF4)

ACP10222

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP10222 Target NameNDUFAF4
Target SynonymsC6orf66; Hormone-regulated proliferation-associated protein of 20 kDa; HRPAP20; HSPC125; My013; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4; NDUF4_HUMAN; Ndufaf4FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-175
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9P032
Background Information
  • Uniprot Id

    Q9P032

  • Target Species

    Human

  • Target Name

    NDUFAF4

  • Target Full Name

    NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

  • Target Function

    Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). May be involved in cell proliferation and survival of hormone-dependent tumor cells. May be a regulator of breast tumor cell invasion.

  • Target Involvement

    Mitochondrial complex I deficiency (MT-C1D)

  • Target Subcellular Location

    Mitochondrion. Membrane; Lipid-anchor.

  • Target Protein Families

    NDUFAF4 family

  • Target Synonyms

    C6orf66; Hormone-regulated proliferation-associated protein of 20 kDa; HRPAP20; HSPC125; My013; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4; NDUF4_HUMAN; Ndufaf4

  • Target Background

    NADH:ubiquinone oxidoreductase (complex I) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. This gene encodes a complex I assembly factor. Mutations in this gene are a cause of mitochondrial complex I deficiency.

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