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| Cat.No | ACP20510 | Target Name | NDUFA10 |
|---|---|---|---|
| Target Synonyms | NDUFA10; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10; mitochondrial; Complex I-42kD; CI-42kD; NADH-ubiquinone oxidoreductase 42 kDa subunit | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 36-355 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O95299 |
|---|
Uniprot Id
O95299
Target Species
Human
Target Name
NDUFA10
Target Full Name
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial
Target Function
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Target Involvement
Leigh syndrome (LS)
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
Complex I NDUFA10 subunit family
Target Synonyms
NDUFA10; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10; mitochondrial; Complex I-42kD; CI-42kD; NADH-ubiquinone oxidoreductase 42 kDa subunit
Target Background
The protein encoded by this gene is a component of 42 kDa complex I, the first enzyme complex in the electron transport chain of mitochondria. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. A mutation in this gene was found in an individual with Leigh syndrome.
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