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| Cat.No | ACP23086 | Target Name | ME1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-572 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P48163 |
|---|
Uniprot Id
P48163
Target Species
Human
Target Name
ME1
Target Full Name
NADP-dependent malic enzyme
Target Subcellular Location
Cytoplasm.
Target Protein Families
Malic enzymes family
Target Tissue Specificity
Expressed in all tissues tested including liver, placenta and white adipose tissue.
Target Synonyms
Cytosolic malic enzyme 1 ; HUMNDME; Malate dehydrogenase ; Malic enzyme 1; Malic enzyme 1; NADP(+) dependent; cytosolic; Malic enzyme 1; soluble ; Malic enzyme; cytoplasmic ; MAOX_HUMAN; ME1; MES; NADP dependent malic enzyme; NADP ME; NADP-dependent malic enzyme; NADP-ME; Pyruvic malic carboxylase
Target Background
This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.
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